trankimazin 2 mg
trankimazin 2 mg not recommended at any stage of pregnancy. Assess the risk benefit ratio .
- 1 TRANKIMAZIN COMPRESSED, 30 tablets . Marketed (February 09, 2015). Authorized .
- 2 TRANKIMAZIN COMPRESSED, 50 tablets . Marketed (February 09, 2015). Authorized .
- 3 TRANKIMAZIN COMPRESSED, 30 tablets . Not marketed (June 1, 1990). Authorized .
- 4 TRANKIMAZIN 2 mg COMPRESSED, 50 tablets . Not marketed (June 1, 1990). Authorized .
Action and mechanism
Short acting benzodiazepine anxiolytic. It acts by increasing the activity of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter found in the brain, by facilitating its binding to the GABAergic receptor. It has hypnotic, anticonvulsant, sedative, muscle relaxant and amnestic activity, with specific antivity in the crisis of anguish; It also has antidepressant activity.
As anxiolytic its effectiveness is similar to that shown by other benzodiazepines.
It has shown efficacy in the treatment of anxiety attacks, with or without agoraphobia. Reduces the intensity and frequency of panic attacks and reduces anticipatory anxiety. If there is associated depression, the use of the antidepressants 8tricicclicos or SSRIs is preferred, although these have a slower onset of action than alprazolam.
The symptoms of withdrawal of the drug can be especially pronounced in case of abrupt interruption of the treatment.
It shows significant interactions with other drugs that are metabolized via hepatic cytochrome P-450.